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Expert Guidance for the Treatment of DLBCL

Tool

Use this Interactive Decision Support Tool to compare your choice of therapy for patients with DLBCL with those of 5 renowned experts.

Released: January 22, 2026

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Provided by Clinical Care Options, LLC dba Decera Clinical Education

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Supporters

Supported by an educational grant from AstraZeneca.

AstraZeneca

Target Audience

This activity is intended for hematologists, oncologists, and other healthcare professionals caring for patients with DLBCL.

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Evaluate emerging evidence for novel treatments for DLBCL and their potential application to clinical practice

  • Educate colleagues and patients on the mechanism of action and clinical rationale for novel agents and combination therapies in DLBCL

  • Select optimal treatments for patients with previously untreated DLBCL, considering expert recommendations along with available efficacy and safety evidence

  • Recommend clinical trials evaluating novel treatments for eligible patients with DLBCL

Disclosure

Primary Author

Jeremy S. Abramson, MD, MMSc: consultant/advisor/speaker: AbbVie, ADC Therapeutics, AstraZeneca, BeiGene, Bristol Myers Squibb, Foresight Diagnostics, Genentech, Gilead, Interius, Johnson & Johnson, Lilly, Miltenyi, Novartis, Roche, Seagen; researcher: Allogene, Bristol Myers Squibb, Cellectis, Genentech, Merck, Mustang Bio, Regeneron, Seagen, Takeda.

John N. Allan, MD: consultant/advisor/speaker: AbbVie, Adaptive Biotechnologies, ADC Therapeutics, AstraZeneca, BeOne, Genentech, Janssen, Lilly, Merck, NeoGenomics, Pharmacyclics; researcher: BeOne, Bristol Myers Squibb, Genentech.

Brad Kahl, MD: consultant/advisor/speaker: AbbVie, AstraZeneca, BeOne, Genentech, Incyte, Lilly, Merck, Pfizer, Roche.

Krish Patel, MD: researcher (paid to institution): AbbVie, Adaptive, Adicet, Arvinas, AstraZeneca, Bristol Myers Squibb, CRISPR Therapeutics, Fate, Genenetech/Roche, Indapta, Janssen, Kite, Lilly, Loxo Oncology, MEI Pharma, Merck, Nuriz, Pfizer, Pharmacyclics, Sana, Xencor; consultant/advisor (paid to institution): AbbVie, AstraZeneca, Avencell, BeOne, Bristol Myers Squibb, Caribou Biosciences, Century Therapeutics, Genentech/Roche, Janssen, Lilly, Lyell Immunopharma, Merck, Sanofi; consultant/advisor: AbbVie, ADC Therapeutics, AstraZeneca, BeiGene, Bristol Myers Squibb, Caribou Biosciences, Genentech/Roche, Kite, Lilly, Merck, Pfizer; speaker: Bristol Myers Squibb, Kite.

Laurie H. Sehn, MD, MPH: consultant/advisor/speaker: AbbVie, AstraZeneca, BeiGene, Bristol Myers Squibb, Cargo, Chugai, Genmab, Incyte, Janssen, Kite/Gilead, Lilly, Merck, Roche/Genentech, Seagen; researcher (paid to institution): Roche/Genentech.